Phototherapy and radiotherapy for skin disease
Narrowband UVB, PUVA and UVA1, how a course is dosed and judged, skin cancer risk by modality, and when superficial radiotherapy or electrons treat skin cancer, CTCL and keloids, with radiation dermatitis grading and the patients who shouldn't be irradiated.
Tier 2Medical sciences concept
Written with AI assistance and fact-checked against the sources below. For exam study, not clinical decisions. How notes are made
At a glance
- Phototherapy uses ultraviolet light to suppress skin inflammation. Narrowband UVB (NB-UVB) is the workhorse for psoriasis, atopic dermatitis, vitiligo, polymorphic light eruption hardening, early mycosis fungoides and uraemic or cholestatic itch.
- It needs a hospital or private unit visit 2 to 3 times a week for months, which is the main barrier in rural and remote Australia.
- Radiotherapy in dermatology mostly means superficial or orthovoltage X-rays, or electrons, for keratinocyte cancer in patients who can't or won't have surgery, adjuvant treatment, cutaneous lymphoma, and post-excision keloids.
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Sources
- Goulden V et al. British Association of Dermatologists and British Photodermatology Group guidelines for narrowband ultraviolet B phototherapy 2022. Br J Dermatol 2022;187:295-308British Association of Dermatologists, 2022 (no newer edition found, November 2026)
- Fowler JC et al. Mutation burden of narrowband ultraviolet B phototherapy (NB-UVB) in human skin: relevance to NB-UVB lifetime exposures and skin cancer surveillance. Br J Dermatol 2025;193:718-28British Journal of Dermatology, 2025
- Medicare Benefits Schedule item 14050: UVA or UVB phototherapy in a whole body or hand and foot cabinetAU/NZAustralian Government Department of Health, Disability and Ageing (MBS Online), Checked November 2026
- Clinical practice guidelines for keratinocyte cancer (radiotherapy chapters)AU/NZCancer Council Australia (NHMRC-approved), 2019 living guideline (no newer edition found, November 2026)
- Balermpas P et al. Expert opinion: radiotherapy for basal cell carcinoma. Recommendations from the DEGRO Dermatooncology Working Group. Strahlenther Onkol 2026;202:451-5German Society for Radiation Oncology (DEGRO), 2026
- Therapeutic Guidelines: Dermatology (psoriasis, atopic dermatitis, vitiligo)AU/NZTherapeutic Guidelines Limited (eTG complete), Version 5, 2022 (no newer edition found, November 2026)
- Last updated
- 14 November 2026
What changed
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