Cannabis and hallucinogens

At a glance

• Cannabis rarely causes life-threatening toxicity in adults. Its harms are psychosis, cannabis use disorder, cannabinoid hyperemesis, road trauma and harm to the developing brain and fetus.
• Synthetic cannabinoids behave like a different drug: seizures, arrhythmia, AKI and agitation.
• The hallucinogenic toxidrome is altered perception with largely preserved orientation. Severe sympathomimetic features, seizures or hyperthermia suggest an NBOMe, a stimulant, or serotonin toxicity.