Pre-chemotherapy screening investigations

At a glance

• Screening before systemic therapy answers four questions: can the patient tolerate it (organ function, performance status), will it reactivate something (HBV, Strongyloides, TB), does a gene or baseline test change the dose (DPYD, eGFR, LVEF), and what must happen before day 1 (fertility, pregnancy test, dental work, vaccines, venous access).
• Each eviQ protocol lists its own pre-treatment evaluation. This note covers the logic so you can work out the list for any regimen.
• Most of it is time-critical but shouldn't delay urgent treatment. Hepatitis B results, for example, can follow the first dose if prophylaxis starts promptly.