Gastroenterology and hepatology
Coeliac disease
Immune enteropathy triggered by gluten in HLA-DQ2 or DQ8 carriers. Who to test, serology on a gluten-containing diet, why adults still need duodenal biopsy in Australia, gluten challenge, the gluten-free diet, follow-up, and non-responsive and refractory disease.
Tier 1Condition
Written with AI assistance and fact-checked against the sources below. For exam study, not clinical decisions. How notes are made
At a glance
- A chronic immune enteropathy triggered by gluten (wheat, barley, rye, and oats in some people) in people carrying HLA-DQ2 or DQ8.
- About 1 in 70 Australians has it, and most aren't diagnosed.
- Test with serology while eating gluten. In Australian adults, diagnosis still needs duodenal biopsy.
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Finished reading?
Sources
- Coeliac Australia: Testing for coeliac disease, Gluten challenge and Ongoing management (health professional pages)AU/NZCoeliac Australia
- Therapeutic Guidelines: Gastrointestinal (eTG complete), coeliac diseaseAU/NZTherapeutic Guidelines Limited
- Rubio-Tapia A et al. American College of Gastroenterology Guidelines Update: Diagnosis and Management of Celiac Disease. Am J Gastroenterol 2023;118:59-76American College of Gastroenterology, 2023
- Al-Toma A et al. European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten-related disorders. United European Gastroenterol J 2019;7:583-613European Society for the Study of Coeliac Disease, 2019
- Husby S et al. European Society for Paediatric Gastroenterology, Hepatology and Nutrition guidelines for diagnosing coeliac disease 2020. J Pediatr Gastroenterol Nutr 2020;70:141-156ESPGHAN, 2020
- Last updated
- 14 November 2026
What changed
- 14 November 2026 Personal emails, About story and Australian-style copy