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Endocrinology

Hypoglycaemia

Treating a hypo, sulfonylurea and insulin hypos, impaired awareness and driving, and working up hypoglycaemia in someone without diabetes (Whipple triad, insulin and C-peptide).

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At a glance

  • In diabetes, hypoglycaemia is a treatment side effect, mainly of insulin and sulfonylureas. It is the commonest diabetes emergency.
  • Without diabetes, only investigate if the Whipple triad is met. Most patients with vague post-meal symptoms don't have true hypoglycaemia.
  • Treat first, then find out why. In a non-diabetic patient, take a sample during the hypo if you can, because it holds the diagnosis.

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Sources

Last updated
14 November 2026
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